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Alternate day fasting increases LDL particle size independently of dietary fat content in obese humans

10.1146/annurev-arplant-042809-112152 Annu

While the more obvious route would be directly suppressing TNF, that might not be a good idea because of its important roles in fighting infections and other invaders, which is already a concern for current treatments, they say

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As humans age, we lose about 50 percent of our NAD+ levels, interfering with our bodys ability to repair cells and protect them from oxidative damage